Author’s response to reviews Title: Mapping mitochondrial heteroplasmy in a Leydig tumor by laser capture micro-dissection and denaturing capillary electrophoreses Authors:
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چکیده
Title: Mapping mitochondrial heteroplasmy in a Leydig tumor by laser capture micro-dissection and denaturing capillary electrophoreses Authors: Paulo Refinetti ([email protected];[email protected]) Christian Arstad ([email protected]) William Thilly ([email protected]) Stephan Morgenthaler ([email protected]) Per Ekstrom ([email protected]) Version: 1 Date: 19 Feb 2017 Author’s response to reviews: Dear Editor and reviewers,
منابع مشابه
Mapping mitochondrial heteroplasmy in a Leydig tumor by laser capture micro-dissection and cycling temperature capillary electrophoresis
BACKGROUND The growth of tumor cells is accompanied by mutations in nuclear and mitochondrial genomes creating marked genetic heterogeneity. Tumors also contain non-tumor cells of various origins. An observed somatic mitochondrial mutation would have occurred in a founding cell and spread through cell division. Micro-anatomical dissection of a tumor coupled with assays for mitochondrial point m...
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تاریخ انتشار 2017